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Hunig's Base



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Auxiliary reagent in organic synthesis

Proton acceptor/scavenger

Replaces Triethylamine and Dimethyl Aniline

Low nucleophilicity

Low self alkylation

Low water solubility


Increases process efficiency

Reduces process costs

Peptide Synthesis


Some types of reaction requiring an auxiliary base


Recovery & Recycle

Recovery and recycle of N,N-Diisopropylethylamine is relatively straightforward because of its low solubility in water.

N,N-Diisopropylethylamine can be simply extracted from water-immiscible organic reaction media, as its salt, in the aqueous phase.

Alternatively, separation as the azeotrope, which layers into 99.8% purity N,N-Diisopropylethylamine and a water phase containing 0.4% of N,N-Diisopropylethylamine, gives high purity, recovered reagent.

Full recycling process details are available from Whyte Chemicals under license to our customers.


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Last modified: April 03, 2001